Publications
2018
- Sarah Eagleman, Don A Vaughn, David R Drover, Caitlin M Drover, Mark Steven Cohen, Nicholas Ouellette, M Bruce MacIver. Do complexity measures of frontal EEG distinguish loss of consciousness in geriatric patients under anesthesia? Front. Neurosci., 20 September 2018.
- Eagleman SL, MacIver MB. Can you hear me now? Information processing in primary auditory cortex at loss of consciousness. British journal of anaesthesia. 2018; 121(3):526-529.PMID: 30115247
- Eagleman SL, Drover CM, Drover DR, Ouellette NT, MacIver MB. Remifentanil and Nitrous Oxide Anesthesia Produces a Unique Pattern of EEG Activity During Loss and Recovery of Response.Frontiers in human neuroscience. 2018; 12:173
2017
- Ouyang YB, Ning S, Adler JR, Maciver B, Knox SJ, Giffard R. Alteration of Interneuron Immunoreactivity and Autophagic Activity in Rat Hippocampus after Single High-Dose Whole-Brain Irradiation.Cureus. 2017; 9(6):e1414.
- Dagne BA, Sunay MK, Cayla NS, Ouyang YB, Knox SJ, Giffard RG, Adler JR, Maciver B. High Dose Gamma Radiation Selectively Reduces GABAA-slow Inhibition.Cureus. 2017; 9(3):e1076.
2016
- Bland BH, Bland CE, MacIver MB. Median raphe stimulation-induced motor inhibition concurrent with suppression of type 1 and type 2 hippocampal theta. Hippocampus. 2016; 26(3):289-300.
2015
- MacIver MB. Mind and Brain: Consciousness in Unresponsive Subjects. Current biology : CB. 2015; 25(23):R1140-2.
2014
- MacIver MB. Bland BH. Chaos analysis of EEG during isoflurane-induced loss of righting in rats. Frontiers in systems neuroscience. 2014; 8:203.
- MacIver MB. Anesthetic agent-specific effects on synaptic inhibition. Anesthesia and analgesia. 2014; 119(3):558-69. NIHMSID: NIHMS595334
Older
- Trudell JR, Bertaccini E, Maciver MB. Teaching an old GABA receptor new tricks. Anesthesia and analgesia. 2012; 115(2):270-3. NIHMSID: NIHMS382714
- Maciver MB, Bronte-Stewart HM, Henderson JM, Jaffe RA, Brock-Utne JG. Human subthalamic neuron spiking exhibits subtle responses to sedatives. Anesthesiology. 2011; 115(2):254-64.
- MacIver MB. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2009; 34(10):2296-304. NIHMSID: NIHMS114953
- MacIver MB. Abused inhalants enhance GABA-mediated synaptic inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2009; 34(10):2296-304. NIHMSID: NIHMS114953
- Bieda MC, Su H, Maciver MB. Anesthetics discriminate between tonic and phasic gamma-aminobutyric acid receptors on hippocampal CA1 neurons. Anesthesia and analgesia. 2009; 108(2):484-90. NIHMSID: NIHMS87297
- Sceniak MP, Maciver MB. Slow GABA(A) mediated synaptic transmission in rat visual cortex. BMC neuroscience. 2008; 9:8.
- Sceniak MP, Maciver MB. Cellular actions of urethane on rat visual cortical neurons in vitro. Journal of neurophysiology. 2006; 95(6):3865-74.
- Sceniak MP, MacIver MB. Anesthesia in silico. Anesthesiology. 2006; 104(3):400-2.
- Winegar BD, MacIver MB. Isoflurane depresses hippocampal CA1 glutamate nerve terminals without inhibiting fiber volleys. BMC neuroscience. 2006; 7:5.
- Lukatch HS, Kiddoo CE, Maciver MB. Anesthetic-induced burst suppression EEG activity requires glutamate-mediated excitatory synaptic transmission. Cerebral cortex (New York, N.Y. : 1991). 2005; 15(9):1322-31.
- Pittson S, Himmel AM, MacIver MB. Multiple synaptic and membrane sites of anesthetic action in the CA1 region of rat hippocampal slices. BMC neuroscience. 2004; 5:52.
- Gredell JA, Turnquist PA, Maciver MB, Pearce RA. Determination of diffusion and partition coefficients of propofol in rat brain tissue: implications for studies of drug action in vitro. British journal of anaesthesia. 2004; 93(6):810-7.
- Bieda MC, MacIver MB. Major role for tonic GABAA conductances in anesthetic suppression of intrinsic neuronal excitability. Journal of neurophysiology. 2004; 92(3):1658-67.
- Lingamaneni R, Krasowski MD, Jenkins A, Truong T, Giunta AL, Blackbeer J, MacIver MB, Harrison NL, Hemmings HC Jr. Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia.
Anesthesiology. 2001; 94(6):1050-7. - Nishikawa K, MacIver MB. Agent-selective effects of volatile anesthetics on GABAA receptor-mediated synaptic inhibition in hippocampal interneurons. Anesthesiology. 2001; 94(2):340-7.
- Nishikawa K, MacIver MB. Membrane and synaptic actions of halothane on rat hippocampal pyramidal neurons and inhibitory interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2000; 20(16):5915-23.
- Rabinovici GD, Lukatch HS, MacIver MB. Hypoglycemic and hypoxic modulation of cortical micro-EEG activity in rat brain slices. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2000; 111(1):112-21.
- Nishikawa K, MacIver MB. Excitatory synaptic transmission mediated by NMDA receptors is more sensitive to isoflurane than are non-NMDA receptor-mediated responses. Anesthesiology. 2000; 92(1):228-36.
- Mikulec AA, Pittson S, Amagasu SM, Monroe FA, MacIver MB. Halothane depresses action potential conduction in hippocampal axons.Brain research. 1998; 796(1-2):231-8.
- Hagan CE, Pearce RA, Trudell JR, MacIver MB. Concentration measures of volatile anesthetics in the aqueous phase using calcium sensitive electrodes. Journal of neuroscience methods. 1998; 81(1-2):177-84.
- Lukatch HS, Echon RM, MacIver MB, Werchan PM. G-force induced alterations in rat EEG activity: a quantitative analysis. Electroencephalography and clinical neurophysiology. 1997; 103(5):563-73.
- Lukatch HS, MacIver MB. Voltage-clamp analysis of halothane effects on GABA(A fast) and GABA(A slow) inhibitory currents. Brain research. 1997; 765(1):108-12.
- Lukatch HS, MacIver MB. Physiology, pharmacology, and topography of cholinergic neocortical oscillations in vitro. Journal of neurophysiology. 1997; 77(5):2427-45.
- Maclver MB, Mikulec AA, Amagasu SM, Monroe FA. Volatile anesthetics depress glutamate transmission via presynaptic actions. Anesthesiology. 1996; 85(4):823-34
- Lukatch HS, MacIver MB. Synaptic mechanisms of thiopental-induced alterations in synchronized cortical activity. Anesthesiology. 1996; 84(6):1425-34.
- MacIver MB, Mandema JW, Stanski DR, Bland BH.
Thiopental uncouples hippocampal and cortical synchronized electroencephalographic activity. Anesthesiology. 1996; 84(6):1411-24. - Mikulec AA, Lukatch HS, Monroe FA, MacIver MB. Diltiazem spares corneal A delta mechano and C fiber cold receptors and preserves epithelial wound healing. Cornea. 1995; 14(5):490-6.
- MacIver MB, Tanelian DL. Structural and functional specialization of A delta and C fiber free nerve endings innervating rabbit corneal epithelium. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1993; 13(10):4511-24.
- MacIver MB, Tanelian DL. Free nerve ending terminal morphology is fiber type specific for A delta and C fibers innervating rabbit corneal epithelium. Journal of neurophysiology. 1993; 69(5):1779-83.
- Tanelian DL, Kosek P, Mody I, MacIver MB. The role of the GABAA receptor/chloride channel complex in anesthesia. Anesthesiology. 1993; 78(4):757-76.
- MacIver MB, Tanelian DL. Activation of C fibers by metabolic perturbations associated with tourniquet ischemia. Anesthesiology. 1992; 76(4):617-23.
- Savola MK, MacIver MB, Doze VA, Kendig JJ, Maze M. The alpha 2-adrenoceptor agonist dexmedetomidine increases the apparent potency of the volatile anesthetic isoflurane in rats in vivo and in hippocampal slice in vitro. Brain research. 1991; 548(1-2):23-8.
- Tanelian DL, MacIver MB. Analgesic concentrations of lidocaine suppress tonic A-delta and C fiber discharges produced by acute injury. Anesthesiology. 1991; 74(5):934-6.
- Mody I, Tanelian DL, MacIver MB. Halothane enhances tonic neuronal inhibition by elevating intracellular calcium. Brain research. 1991; 538(2):319-23.
- MacIver MB, Tanelian DL, Mody I. Two mechanisms for anesthetic-induced enhancement of GABAA-mediated neuronal inhibition. Annals of the New York Academy of Sciences. 1991; 625:91-6.
- Tanelian DL, MacIver MB. Differential excitatory and depressant anesthetic effects on mammalian A-delta and C fiber sensory afferents. Annals of the New York Academy of Sciences. 1991; 625:273-5.
- MacIver MB, Kendig JJ. Anesthetic effects on resting membrane potential are voltage-dependent and agent-specific. Anesthesiology. 1991; 74(1):83-8.
- Kendig JJ, MacIver MB, Roth SH. Anesthetic actions in the hippocampal formation. Annals of the New York Academy of Sciences. 1991; 625:37-53.
- Jarvis D, MacIver MB, Tanelian DL. Electrophysiologic recording and thermodynamic modeling demonstrate that helium-neon laser irradiation does not affect peripheral Adelta- or C-fiber nociceptors.Pain. 1990; 43(2):235-42.
- Tanelian DL, MacIver MB. Simultaneous visualization and electrophysiology of corneal A-delta and C fiber afferents. Journal of neuroscience methods. 1990; 32(3):213-22.
- MacIver MB, Tanelian DL. Volatile anesthetics excite mammalian nociceptor afferents recorded in vitro. Anesthesiology. 1990; 72(6):1022-30.
- MacIver MB, Kendig JJ.Enflurane-induced burst discharge of hippocampal CA1 neurones is blocked by the NMDA receptor antagonist APV. British journal of anaesthesia. 1989; 63(3):296-305.
- MacIver MB, Tauck DL, Kendig JJ. General anaesthetic modification of synaptic facilitation and long-term potentiation in hippocampus. British journal of anaesthesia. 1989; 62(3):301-10.
- Kendig JJ, Grossman Y, MacIver MB. Pressure reversal of anaesthesia: a synaptic mechanism. British journal of anaesthesia. 1988; 60(7):806-16.
- MacIver MB, Roth SH. Inhalation anaesthetics exhibit pathway-specific and differential actions on hippocampal synaptic responses in vitro. British journal of anaesthesia. 1988; 60(6):680-91.
- Konopacki J, Bland BH, MacIver MB, Roth SH. Cholinergic theta rhythm in transected hippocampal slices: independent CA1 and dentate generators. Brain research. 1987; 436(2):217-22.
- MacIver MB, Roth SH. Anesthetics produce differential actions on membrane responses of the crayfish stretch receptor neuron. European journal of pharmacology. 1987; 141(1):67-77.
- Konopacki J, MacIver MB, Bland BH, Roth SH.Carbachol-induced EEG ‘theta’ activity in hippocampal brain slices. Brain research. 1987; 405(1):196-8.
- MacIver MB, Roth SH. Enflurane-induced burst firing of hippocampal CA 1 neurones. In vitro studies using a brain slice preparation. British journal of anaesthesia. 1987; 59(3):369-78.
- MacIver MB, Roth SH. Barbiturate effects on hippocampal excitatory synaptic responses are selective and pathway specific. Canadian journal of physiology and pharmacology. 1987; 65(3):385-94.
- Konopacki J, Maciver MB, Bland BH, Roth SH. Theta in hippocampal slices: relation to synaptic responses of dentate neurons. Brain research bulletin. 1987; 18(1):25-7.
- Roth SH, MacIver MB. Pathway specific and differential effects produced by halothane on hippocampal neurons in vitro. Proceedings of the Western Pharmacology Society. 1986; 29:163-6.
- MacIver MB, Harris DP, Konopacki J, Roth SH, Bland BH. Carbachol induced rhythmical slow wave activity recorded from dentate granule neurons in vitro. Proceedings of the Western Pharmacology Society. 1986; 29:159-61.
- MacIver MB, Roth SH. The effects of temperature on neuronal excitability. Proceedings of the Western Pharmacology Society. 1982; 25:427-31.
- MacIver MB, Damson E, Tan KS, Roth SH. A simple and sensitive force transducer suitable for measuring tensions in small muscle fibers. Journal of pharmacological methods. 1981; 5(2):93-8.
- MacIver MB, Roth SH. Effects of halothane on the neuronal output, membrane properties and synaptic transmission of an isolated neuron. Proceedings of the Western Pharmacology Society. 1980; 23:405-11.